The smell of homemade bread on Sunday mornings. Wholesome. Comforting. Safe.
Except it's not.
Every time you eat bread, pasta, crackers, or any product made from wheat, you're triggering inflammatory processes that damage your gut lining, dysregulate your immune system, and contribute to chronic disease.
Heart disease. Autoimmune conditions. Brain disorders. Joint pain. Fibromyalgia. Depression and anxiety. Chronic fatigue. MS. ALS.
Wheat doesn't cause all of these conditions. But it plays a significant role in most of them—either as a primary trigger or as an aggravating factor that prevents healing.
Here's why wheat is a problem and what you need to know about gluten, celiac disease, and gluten sensitivity.
Gluten is a protein found in wheat, rye, barley, and oats. The name comes from Greek and Latin, meaning "glue"—it's the protein that holds dough together and gives bread its chewy texture.
High-gluten flours make better pizza dough and artisan bread. They also create more severe inflammatory responses in the human gut.
The problematic component: Gliadin, a fraction of gluten found in wheat, rye, barley, and oats. This is the protein that triggers immune reactions and intestinal damage.
Celiac disease is an inherited genetic disorder. When someone with celiac consumes gluten, the gliadin protein acts as an antigen and combines with antibodies to form immune complexes in the intestinal lining.
This triggers killer (K) lymphocytes—immune cells that attack and destroy the villi (finger-like projections in the small intestine that absorb nutrients).
Result: Mucosal damage, chronic inflammation, malabsorption, and nutrient deficiencies.
Symptoms:
Celiac can manifest at any age—infancy, childhood, or adulthood. It often goes undiagnosed for years because symptoms are attributed to other conditions.
Traditional diagnosis: Intestinal biopsy. The problem: if the biopsy doesn't sample a damaged section of the intestine, you get a false negative. You're told you're fine when you're not.
Better diagnostic methods:
Approximately 3 million Americans have diagnosed celiac disease. The actual number is likely much higher due to underdiagnosis.
This is far more common than celiac disease. In clinical practice, 80-90% of people test positive for gluten sensitivity.
Gluten sensitivity is acquired, not inherited. It develops over time through:
Unlike celiac disease, gluten sensitivity doesn't destroy villi. But it creates chronic inflammation, immune activation, and systemic symptoms that degrade health over time.
Symptoms overlap with celiac:
The key difference: celiac is autoimmune and permanent. Gluten sensitivity is inflammatory and potentially reversible with gut healing—though most people remain sensitive long-term once the reaction develops.
Gluten doesn't just affect your gut. It triggers mechanisms that create inflammation throughout your entire body.
Gliadin triggers the release of zonulin, a protein that opens tight junctions between intestinal cells. This increases intestinal permeability (leaky gut).
Once the barrier is compromised, partially digested food proteins, bacterial endotoxins, and other inflammatory compounds enter the bloodstream. Your immune system attacks them, creating systemic inflammation.
This is why gluten sensitivity manifests as brain fog, joint pain, skin issues, and autoimmune conditions—not just digestive symptoms.
Read more: What Causes a Food Allergy
The molecular structure of gliadin resembles proteins in your thyroid, cerebellum, and other tissues. When your immune system creates antibodies against gliadin, those antibodies sometimes attack your own tissues (molecular mimicry).
This contributes to:
When gluten is digested, it produces gluteomorphins—peptides with opioid-like activity. These cross the blood-brain barrier and bind to opioid receptors in the brain.
Result: addictive cravings for bread and pasta, mood changes, brain fog, and cognitive dysfunction.
This is why people say they're "addicted to bread." They actually are, neurologically.
Avoiding wheat means eliminating more than just bread and pasta.
The wheat family includes:
Foods containing wheat/gluten:
Hidden sources:
Reference guide: A to Z Guide to the Foods that Contain Your Food Allergies
Don't trust "gluten-free" packaged foods.
Most are highly processed, made with rice flour, corn starch, potato starch, and tapioca—refined carbohydrates that spike blood sugar and create their own inflammatory problems.
They're also often loaded with seed oils, sugar, and additives to mimic the texture and taste of wheat products.
You're trading one inflammatory trigger for several others.
1. Complete elimination for 12-18 months.
Remove all wheat, rye, barley, oats, and gluten-containing grains. This gives your gut time to heal.
After 12-18 months of strict avoidance and gut repair, some people with gluten sensitivity (not celiac) can tolerate small amounts of gluten occasionally. But most remain sensitive long-term.
2. Heal intestinal permeability.
Gluten damaged your gut barrier. Repair requires:
3. Restore gut bacteria.
Gluten-induced inflammation disrupts the microbiome. Rebuilding requires:
4. Support immune regulation.
Chronic immune activation doesn't shut off immediately when you remove gluten. Support requires:
For comprehensive guidance on anti-inflammatory eating and gut healing, visit the Fuel Your Body pillar page.
Wheat isn't food. It's an inflammatory trigger masquerading as nutrition.
The USDA food pyramid told you to eat 6-11 servings of grains daily. That recommendation created an epidemic of obesity, diabetes, autoimmune disease, and chronic inflammation.
You don't need grains. Your body doesn't need grains. Every nutrient in wheat is available in higher quantities and more bioavailable forms from meat, vegetables, and other whole foods.
Remove wheat entirely. See what your body does when you stop poisoning it three times a day.
Struggling with chronic symptoms despite "eating healthy"? Dr. JJ Gregor uses Applied Kinesiology to identify gluten sensitivity and other hidden food reactions in his Frisco, Texas practice. Schedule a consultation to uncover what's driving your symptoms.
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